Karrigan was born Karrigan Kate Powers in Gainesville, FL. She grew up in Central Florida, where she lived with her five siblings, two dogs, and many foster babies. Karrigan studied dance from the age of four years old, started commercial and Theatre acting at seven years old. It was not long before she entered the world of independent and short films. Karrigan appeared in Lionsgate's Film "Turtle Tale" as Young Camper. At the age of eight years old, Karrigan auditioned for and landed the role of Young Meg Rayburn in Netflix's "Bloodline" series.