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Inspired by the spine-chilling story of India's first woman serial killer, KD Kempamma alias Cyanide Mallika. Frustrated by lower middle-class lifestyle, she starts targeting innocent women visiting temples and kills them using cyanide before robbing valuables from them. Cyanide Mohan is another serial killer who lures young unmarried girls with a marriage proposal only to kill them with cyanide after having sex with them. Two cold-blooded killers end up meeting and the rest of the plot revolves around how they try to outsmart each other.