The film deals with heavy topics including grief, digital technology encroaching on the intimacy of human life, bullying, corporate greed, death, neighbourhood feuds and explosions.
There are some brief shots of bloody bodies and dying people which may frighten and disturb some viewers. This includes a boy with behavioral problems rolling down a hill and being struck by a car, two dead men in an elevator covered in blood, and other instances.
There are some emotionally uncomfortable (but not shocking or scary) scenes, such as a woman fiddling on her smartphone instead of paying any attention to her niece, a neighbour loudly pounding on windows and shouting, and a man verbally bullying his employees.
The death of a pet is mentioned once in a toy commercial, and later on numerous times after a woman's dog goes missing.
One of the themes in the film is the oversaturation of digital technology in human life. Viewers see numerous smartphones, an AI home assistant, AI toys and other things that can be quite uncomfortable and intense. At one point a child whose parents are killed is ignored by her aunt, who is constantly playing with a smartphone. An AI home assistant turns on and frightens the child.
A subplot involves a nasty woman who owns a vicious dog. The fight between neighbours, coupled with a child being bitten (drawing blood) and M3GAN having her neck bitten and dragged through the fence can be quite disturbing, especially when the police refuse to do anything about the dog and the bitten child develops a fever from the bite.
A child breaks down sobbing over the loss of her parents and M3GAN comforts her. The scene is quite visceral and intense, although it is one of the film's more placid moments.
A woman refuses to let her traumatized niece play with a toy (it's a "collector's item") until a social worker comes to visit. The scene is somewhat tense and uncomfortable.