We see Sam's husband, wounded and dying in a rainy alley after being mugged. By way of both animation and live action we see bullets fly.
In prison, Joe gets into a brawl, battering several inmates with repeated and vicious blows to the head while trying to protect an old man. (Blood covers one man's face.)
The elderly prisoner has his palm sliced open with a knife (onscreen). As mentioned, Keisha is accidentally hit by a car (offscreen).
A young Joe is bitten by a rattlesnake. Sam attempts to help him to safety, but he collapses from the effect of the venom.
In grade school, Joe punches out a bully who's pushing Sam around.
We see Joe's blood staining the side of his shirt, and later he's unconscious in a pool of his own blood because of his failing kidneys.
We're told a brief story of Keisha watching her mother's murder. We see her hiding in a cabinet in a burning kitchen.
Sam sits with a gun, contemplating suicide. She goes so far as putting it up to her chin. (The film points out what a foolish waste that choice would have been.)