The entire movie is based about a drug-dealer and his friend finding Hill billy highway, which is promises "acres of weed"
The movies credits at the beginning are spelled out in untreated toke
A highway is named Route:420
A bong is shown being smoked from the man's point of view
The characters smoke pot in almost every scene
A cartoon is shown as a weed joke
The characters are drug-dealers
A police helicopter flies over a field of burning pot, the pilot and co-pilot are shown getting high off it
A bunch of DEA agents and police officers get high off a burning field of weed
A man smokes an over-sized blunt
A man excretes weed
A car is shown foggy from the characters smoking weed
A man runs a dispensery
Weed jokes throughout
Multiple songs about weed use
The main characters stay with weed farmers
A man "Lives with one with the toke"
A cartoon is named master Kush and sports the slogan "One more toke"