Garfield is often seen cross dressing in some episodes, which is played for laughs.

Jon and Liz are officially a couple in this show. They usually have romantic dates.

There was a girl cat Garfield presumably dated in the past.

The main character or other characters can get harmed in comical ways, wether it's getting crushed, or hit with an object, but for the most part, the violence happens off-screen.

Cartoon violence

Jon Arbuckle's small twin nieces often call Garfield "Kitty Cat" (referring to a feline), which can be heard as a slang term for a female's genitalia.

In one episode Garfield calls Jon a Cad, a term for someone who "doesn't cut it as a gentleman" and is an insult that is generally sexual in origin. In another episode, Garfield calls Nermal a "wiener head" which is of course comparing the cats head to male genitalia which is more commonly known as a penis. To make this insult even more offensive, Nermal's head does bear striking resemblance to said genitalia.

Frequent usage of the word shit, infrequent usage of the word fuck, and the occasional usage of the word damn.

In season 2 episode 4 when Jon has a date with Liz wine is seen

Some episodes have horror themes.

Garfield will get himself in horrible situations, but in a comical manner. this is a very clean show, good for kids.