Some female nudity - topless mainly.

A rape scene takes place.

Two puppies are killed on-screen with graphic results and later eaten by freaks, upsetting the main character.

A girl can be seen tearing a roosters eye out with her teeth.

A girl finds the corpse of her mother being eaten by rats.

Strong gory violence. Some of it is fantastical but may be disturbing to some people.

Some swear words used infrequently.

The animation, art and music is extremely unsettling. The art style is adapted wholesale from a horror manga and looks different to what's normally accepted as anime.

The freaks torment, rape and abuse Midori through the whole movie. They're among the most heartless anime characters imaginable.

The scene with the puppies being killed and eaten will upset animal lovers.

Numerous surreal sequences and creepy nightmares from Midori's perspective.

The scene where the dwarf kills his audience may be disgusting and disturbing