A truck driver dies in an explosion during a fight between Megamind and Titan/Tighten, however, only the truck is seen exploding. This is not referenced in the film but is implied from the scene.
A woman is threatened with dangerous weapons and implements, including alligators, knives, and guns.
There is cartoon violence, as the superheroes fight each other.
Megamind throws a lit stick of dynamite at his cyborg "children", who end up blowing up.