Some sexual jokes are made throughout the film.

A man's bare buttocks are seen twice.

A man and a woman joke about a threesome.

The main charater runs for an erectile disfunction charity to replace another runner (he is not personally afflicted).

A naked man powders himself (we see him from the back and waist up) in front of another man. He asks, "do you see my point?" during a conversation, and the other man says "Yes, I do," when looking at his penis.

Two men pop a blister on one man's foot by sticking a nail into it.

Some hitting and fighting that results in only a few scrapes and cuts.

Two men have a comic fight, and hit each other in the testicles.

A man trips up another man; one man brakes his ankle, but forces himself to keep running, and the other has a bloody knee but no real damage.

In the uncut version, there are four uses of "fuck"; when Dennis forgets his keys and loudly exclaims "FUCK!" outside his front door; when Mr Goshdashtidar is telling Dennis about his marriage, and he claims the best thing he remembers was all the "fucking"; when Libby shows Gordon to a bathroom, and he says his shoes "hurt like fuck"; and near the end. The cut version and unrated version has one f-word which is the part when a reporter asks Dennis how he feels, and he replies (How the fuck do you think I feel?). A couple of these were edited out for most versions.

In the cut version, there is one use of the word (fuck).

"Asshole", "bastard", "shithead", "cock" and "prick" are all used as insults.

"Shit", "hell", "damn", "ass" and other profanities are used.

Moderate sex references.

A couple of scenes of casual drinking.

Dennis is seen smoking a couple of times.

None.