Some sexual references.

A character talks about being sexually abused as a child (being taught how to French kiss, "among other things") and acting out sexually.

Mentions of prostitution.

A man and woman are playing in a bathtub. It isn't sexual and although they are both naked, nothing is shown.

There are themes relating to a murder, but the actual scene is quick cut, and not graphic. There is a brief image of blood on the floor next to a dying/dead man, and there is talk of cutting up a corpse to dispose of it.

About 30-40 f-words.

Several homophobic slurs.

Ecstasy, Ketamine, and cocaine are used frequently and in a casual manner throughout the film.

Several characters are shown overdosing or experiencing drug withdrawal.