During the narrator's opening monologue where Professor Utonium is seen grocery shopping, a villain from the show is seen robbing the store by pointing an antique flared-end shotgun right in the cashier's face. The gun is never fired or used to hurt anyone.
After learning the rules of the game of tag, the three girls start out slow in playing it, but soon start to speed up and then use their superpowers in playing it and tagging each other as opponents. During this, they unintentionally cause all sorts of property damage at the school and then around the city, including (but not limited to) the following.
One is smashed through the school wall, who in turn then blasts down and then back up through the playground (creating huge holes). A house is damaged and we see trees falling and cars flying up through the air in the background of a shot. A large fire then erupts in the background. They blast through a big billboard sign and tear up the roads or set them on fire as they race down them. Some cars smash into a building and another crashes through a storefront window. They tear up the sides of buildings as they continue playing and cause a huge ball/globe to fall from its perch and cause some damage on the streets below. A car flies through the air and crashes into a guy's apartment. Various explosions also erupt and the girls then smash into a pickle cart, destroying it and knocking various people, including the Mayor, down and/or unconscious.