Frequent strong sexual content, including graphic sexual references.
Sex scenes are rampant in this series that often features a variety of sexual situations. Situations have featured casual sexual relationships, sex with multiple partners, prostitution, and sexual situations such as incest, necrophilia, bestiality, and pedophilia.
Rape is a major theme during Season 3 and 4 due to a serial rapist/killer character called The Carver.
Surgeries revolving around sexual organs are frequent such as breast implants and penis enlargements, as well as genital reconstructive surgeries.
Sexual fetishes often become subject matter explored in the series, such as group sex. In later seasons autoerotic asphyxiation is depicted due to a main character trying it out after hearing of it from a patient.
Nudity in the series is limited to bare buttocks and brief glimpses of bare breasts with the nipples being covered.
Surgical nudity is depicted.