In one episode, a character tells one of the protagonists that he will do "certain things" to two of the other characters to "make them mine"
Nudity is suggested but not shown (the characters who transform into animals are naked when they transform back to humans, but there is always a cloud that obscures details.) Also some mild sexual innuendo (i.e., teasing about a boy being "hot for" a girl, etc.) Certain of the characters are cross-dressers, but this is not much commented on. Because it is a Japanese series, the conventions of dress are different from American TV anyway (i.e., both genders wear kimonos on occasion.)A scene at a hot spring where they are naked but nothing is shown and the boys and girls are separated.