It's implied the girls get very drunk towards the end of the movie
Drugs: None
The Marie's smoke cigarettes along with one of the older men they have dinner with.
Towards the beginning of the film, one of the girls asks a man for a cigarette.
The girls get drunk at a nightclub and proceed to mess with the other attendants.
Attendants at a nightclub are seen smoking cigarettes.
Marie I smokes in a bathroom while Marie II does her makeup. Marie I forces the cigarette into Marie II's mouth, telling her that she must smoke. Marie II shames her for smoking and gives the cigarette back to her.