Sex is never actually depicted on screen but is implied.

There is a scene of a party where the guests are completely nude. This scene is the main reason for the movie's R rating. Depending on which version you see, the nudity varies.

A woman is raped, we see brief glimpses of a man taking control of her and her disturbed reactions.

In the unedited version, there is fairly extensive full frontal and rear female nudity, and some brief male nudity.

The American theatrical release version only shows split-second instances of female breast and rear nudity are visible.

Some verbal insinuations for sexual references.

The opening sequence is composed of disorienting camerawork and distortions of a human face, could be unsettling.

There is a mildly graphic scene of facial plastic surgery, more implicit and hidden with camera angles.

Murder is discussed, though there is no actual blood or gore in the film.

About two uses of damn.

Two uses of hell.

There are several scenes where people drink alcohol, and two scenes where guests become intoxicated, one of which resembles a 'bacchanalia'.

Smoking is depicted often.

The smoking of marijuana is implied in one scene, drugs are used for medical purposes

The end of the film is very disturbing.

This is a very depressing movie.

The nature of the film is quite intense, especially the title sequence which features unusual camera work with close-up distortions of various body parts.