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In Xochimilco 1909, María Candelaria and Lorenzo Rafael long for getting married but the odds are against them. María Candelaria is segregated for being a prostitute's child and the couple faces the greed of Mr. Damian, the town's shop owner who secretly desires María. When María falls sick with Malaria, Lorenzo Rafael steals a quinine bottle from Damian's shop, unleashing tragedy for the lovers.