The Barricade (1921)

Jacob Solomon and Michael Brennan are partners in a cigar store on New York City's East Side. When Michael dies Jacob adopts his son Robert, who grows up to be a prominent physician in his neighborhood. He marries wealthy socialite Jane Stoddard, who convinces him to move out of the East Side and start a practice on swanky Fifth Avenue, where he can make a lot more money. Robert follows his wife's advice, but winds up drifting further and further away from the family and friends he grew up with and who helped him become the man he is.