A man and a woman have sex, and we see glimpses of movement, hear sounds, but no nudity is seen. Later, they kiss passionately and she is in her bra.

It is suggested that a man is performing oral sex on a woman.

A man and a woman have sex on a couch, and we hear a lot of moaning. No nudity is seen.

A man and a woman have sex; he is lying on top of her thrusting, we hear sounds, and her breasts are shown.

We hear that a woman has died, and we see a room covered in blood; suicide is implied.

A man is beaten up off screen.

Many shots of heroin needles going into arms, and some blood in the syringes. In one scene, a man sprays blood from a syringe onto a ceiling.

Overall self-destructive, though not particularly violent behavior of characters throughout.

At least 41 "f" words (1 used with "mother" and 1 used sexually), 24 "s" words, 1 slang term for male genitals ("d*ck"), 7 asses (2 used with "hole"), 2 craps, 1 hell, and 7 uses of "Jesus," 4 of "My God," 3 of "Oh God," and 2 uses each of "G-damn," "God," "Christ" and "Jesus Christ" as exclamations.

The movie deals with heroin addiction, and it is used graphically throughout the movie, including a wince-inducing scene where Ben Stiller's character injects heroin into his neck.

Marijuana is used.

Characters pop pills

Possible crack use

Characters smoke and drink

The whole movie is an extremely graphic and harrowing depiction of drug addiction and how it almost ruins a man's life. Very intense, especially in the latter half.