The episode, "Not Another Monday" deals with a woman wanting to commit suicide.
In the episode Room 7, Blanche attempts suicide to get demolished in her grandmother's house while being handcuffed
If turned into a movie definitely would be PG-13 for crude and sexual humor, thematic elements and for some strong language.
Arguing between characters can be intense and upsetting.
The episodes "Sick and Tired" and "72 Hours" may upset some viewers, because both have a small amount of thematic material in them (that being references to death)
Nothing very frightening is seen throughout the series.