The film has many references to sex and what people are interested in in sex (big breasts, etc.) It's PG-13 level sexual dialogue.

A comical fantasy in which a man chases another man with a knife and kills hims. Not at all realistic and played for laughs with no blood.

Nothing that isn't PG-level.

A lot of talk about alcohol and how drinking it attracts women. A few scenes of smoking cigarettes. Lots of casual drug use (prescription drugs).