Tons of (comedic) sexual dialogue.

S1, There is a CGI render image of a teen stroking a another teen's penis, this file is shown multiple times in the series.

S1, There is a lot of hand drawn images of penises and Vaginas running throughout the series.

S1, The whole series has sexually explicit dialogues and sexual references and implied sex throughout.

S1, A teen is shown making gestures of humping a toy horse, its in a comical sense though.

Extreme high school humor throughout

Fuck, Shit, Cock, and various slang and innuendo's are used frequently and throughout season 1 and 2.

One episode features a surprising amount of underage drinking and drug use at a party (a teenager is mentioned, not seen, to have crushed up Adderall with a spray-paint can).

Poop are shown a lot. Coming back in a lot of different scenes. This can be considered offensive and gross, and can frighten people. It's good to have that in mind while watching season 2

Viewers should keep in mind that this show is a satirical take on true crime shows. So it isn't meant to be taken seriously and meant more for humor.