There are a few scenes where it looks like the teenagers are about to have sex. No nudity.

Lots of jokes regarding sexuality (jokes about sexualities, masturbation, sexual life)

Lots of profanity with Argentinian slang, mostly about sex, insults etc.

Not the main focus of the story but there are parties, drunk people and mentions of other drugs. No explicit use of harder drugs (just cigarettes and beer/ other alcoholic beverages at most).