Blood is common in this supernatural hybrid show. The vampire lead frequently 'feeds' from blood bags that he gets from the hospital he works at. There have been a fair few gory and gruesome scenes (people dying graphically, vampires feeding on humans, the implied ripping apart of people by werewolves).
There are a fair bit of beheadings, stabbings, flesh biting, impaling, and fighting. There's always a large amount of blood shown.
One of the recurring characters of the second season has his skin shaved off (not shown, but his screams are heard and may be disturbing). He is later shown without his skin. This is quite graphic as he is unrecognizable and looks quite disturbing.
It's quite a violent and gory show, portraying a large amount of blood and on-screen violence. But due to the fact that's it's basic cable, a bit of the more gory violence is offscreen.