The Mouse and the Monster (1996)

A wacky animated series about two unlikely pals -- a big, blue, lovable one-eyed monster, Mo," and his reluctant protector, a tiny mouse named Chesbro. Ches and Mo are constantly on the run from Dr. Wackersteen, the crazy scientist who created Mo and now wants to put the brain of a dead pianist in Mo's head! The series follows the adventures of the two best friends as Mo gets them into trouble and Ches gets them out.