Family Guy (1999)

Sick, twisted, and politically incorrect, the animated series features the adventures of the Griffin family. Endearingly ignorant Peter and his homemaker wife Lois reside in Quahog, Rhode Island with their three kids. Meg, their eldest, is a social outcast; teenage Chris is awkward and clueless about girls; and the youngest, Stewie, is a genius baby bent on killing his mother and destroying the world. Their talking dog Brian keeps Stewie in check while sipping martinis and sorting through his own life issues.